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Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein–Gremlin signaling pathways

Slit guidance ligand 2 (SLIT2) is a large, secreted protein that binds roundabout (ROBO) receptors on multiple cell types, including neurons and kidney podocytes. SLIT2-ROBO–mediated signaling regulates neuronal migration and ureteric bud (UB) outgrowth during kidney development as well as glomerula...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tumelty, Kathleen E., Higginson-Scott, Nathan, Fan, Xueping, Bajaj, Piyush, Knowlton, Kelly M., Shamashkin, Michael, Coyle, Anthony J., Lu, Weining, Berasi, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836125/
https://ncbi.nlm.nih.gov/pubmed/29317497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.804021
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