Real-time imaging of yeast cells reveals several distinct mechanisms of curing of the [URE3] prion

The [URE3] yeast prion is the self-propagating amyloid form of the Ure2 protein. [URE3] is cured by overexpression of several yeast proteins, including Ydj1, Btn2, Cur1, Hsp42, and human DnaJB6. To better understand [URE3] curing, we used real-time imaging with a yeast strain expressing a GFP-labele...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhao, Xiaohong, Lanz, Jenna, Steinberg, Danielle, Pease, Tyler, Ahearn, Joseph M., Bezsonov, Evgeny E., Staguhn, Elena D., Eisenberg, Evan, Masison, Daniel C., Greene, Lois E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836123/
https://ncbi.nlm.nih.gov/pubmed/29330300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809079
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