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Serum exosomes can restore cellular function in vitro and be used for diagnosis in dysferlinopathy

Purpose: It is challenging to deliver the full-length dysferlin gene or protein to restore cellular functions of dysferlin-deficient (DYSF(-/-)) myofibres in dysferlinopathy, a disease caused by the absence of dysferlin, which is currently without effective treatment. Exosomes, efficient membranous...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Dong, Xue, Gao, Xianjun, Dai, Yi, Ran, Ning, Yin, HaiFang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835933/
https://ncbi.nlm.nih.gov/pubmed/29507617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.22856
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