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Downregulation of Pim-2 induces cell cycle arrest in the G(0)/G(1) phase via the p53-non-dependent p21 signaling pathway
Pim-2 is a serine/threonine protein kinase that is highly expressed in various types of cancer, with essential roles in the regulation of signal transduction cascades, which promote cell survival and proliferation. The present study demonstrated that Pim-2 was expressed in cells lines derived from h...
Gespeichert in:
| Veröffentlicht in: | Oncol Lett |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835926/ https://ncbi.nlm.nih.gov/pubmed/29541172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7865 |
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