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HDAC inhibitors suppressed small cell lung cancer cell growth and enhanced the suppressive effects of receptor-targeting cytotoxins via upregulating somatostatin receptor II

Small cell lung cancer (SCLC) is a malignant human cancer and patients have very limited benefit from traditional anticancer treatments, with a poor five-year survival rate being 10% less. In present study, we observed that Notch signalling activation induced SCLC cell growth suppression via overexp...

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Библиографические подробности
Опубликовано в: :Am J Transl Res
Главные авторы: Sun, Lichun, He, Quanyong, Tsai, Cheguo, Lei, Jun, Chen, Jing, Vienna Makcey, Lily, Coy, David H
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835820/
https://ncbi.nlm.nih.gov/pubmed/29511449
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