Tamoxifen enhances stemness and promotes metastasis of ERα36(+) breast cancer by upregulating ALDH1A1 in cancer cells

The 66 kDa estrogen receptor alpha (ERα66) is the main molecular target for endocrine therapy such as tamoxifen treatment. However, many patients develop resistance with unclear mechanisms. In a large cohort study of breast cancer patients who underwent surgery followed by tamoxifen treatment, we de...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Res
Main Authors: Wang, Qiang, Jiang, Jun, Ying, Guoguang, Xie, Xiao-Qing, Zhang, Xia, Xu, Wei, Zhang, Xuemin, Song, Erwei, Bu, Hong, Ping, Yi-Fang, Yao, Xiao-Hong, Wang, Bin, Xu, Shilei, Yan, Ze-Xuan, Tai, Yanhong, Hu, Baoquan, Qi, Xiaowei, Wang, Yan-Xia, He, Zhi-Cheng, Wang, Yan, Wang, Ji Ming, Cui, You-Hong, Chen, Feng, Meng, Kun, Wang, Zhaoyi, Bian, Xiu-Wu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2018
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835774/
https://ncbi.nlm.nih.gov/pubmed/29393296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2018.15
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