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The Effect of TNF-α on Regulatory T Cell Function in Graft-versus-Host Disease
FoxP3(+) regulatory T cells (Tregs) are a subset of CD4(+) T cells that can suppress proliferation and effector functions of T cells, B cells, NK cells, and antigen-presenting cells. Treg deficiency causes dramatic immunologic disease in both animal models and humans. As they are capable to suppress...
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| Publié dans: | Front Immunol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835761/ https://ncbi.nlm.nih.gov/pubmed/29541073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00356 |
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