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The Effect of TNF-α on Regulatory T Cell Function in Graft-versus-Host Disease

FoxP3(+) regulatory T cells (Tregs) are a subset of CD4(+) T cells that can suppress proliferation and effector functions of T cells, B cells, NK cells, and antigen-presenting cells. Treg deficiency causes dramatic immunologic disease in both animal models and humans. As they are capable to suppress...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mancusi, Antonella, Piccinelli, Sara, Velardi, Andrea, Pierini, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835761/
https://ncbi.nlm.nih.gov/pubmed/29541073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00356
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