PERK Pathway Activation Promotes Intracerebral Hemorrhage Induced Secondary Brain Injury by Inducing Neuronal Apoptosis Both in Vivo and in Vitro

The protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) signaling pathway was reported to exert an important role in neuronal apoptosis. The present study was designed to investigate the roles of the PERK signaling pathway in the secondary brain injury (SBI) induced by intracerebral hemo...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Meng, Chengjie, Zhang, Juyi, Dang, Baoqi, Li, Haiying, Shen, Haitao, Li, Xiang, Wang, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835756/
https://ncbi.nlm.nih.gov/pubmed/29541018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00111
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