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Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury

Intracerebral hemorrhage (ICH) is a cerebrovascular disease with high mortality and morbidity, and the effective treatment is still lacking. We designed this study to investigate the therapeutic effects and mechanisms of melatonin on the secondary brain injury (SBI) after ICH. An in vivo ICH model w...

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Detalhes bibliográficos
Publicado no:Transl Stroke Res
Main Authors: Wang, Zhong, Zhou, Feng, Dou, Yang, Tian, Xiaodi, Liu, Chenglin, Li, Haiying, Shen, Haitao, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750335/
https://ncbi.nlm.nih.gov/pubmed/28766251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-017-0559-x
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