Translocation of Epidermal Growth Factor (EGF) to the nucleus has distinct kinetics between adipose tissue-derived mesenchymal stem cells and a mesenchymal cancer cell lineage

Nuclear Epidermal Growth Factor Receptor (EGFR) has been associated with worse prognosis and treatment resistance for several cancer types. After Epidermal Growth Factor (EGF) binding, the ligand-receptor complex can translocate to the nucleus where it functions in oncological processes. By three-di...

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Publicado en:J Struct Biol
Main Authors: Faraco, Camila Cristina Fraga, Faria, Jerusa Araújo Quintão Arantes, Kunrath-Lima, Marianna, de Miranda, Marcelo Coutinho, de Melo, Mariane Izabella Abreu, Ferreira, Andrea da Fonseca, Rodrigues, Michele Angela, Gomes, Dawidson Assis
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835415/
https://ncbi.nlm.nih.gov/pubmed/29277356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.12.007
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