Valproic Acid Combined with Zoledronate Enhance γδ T Cell-Mediated Cytotoxicity against Osteosarcoma Cells via the Accumulation of Mevalonate Pathway Intermediates

The long-term survival of osteosarcoma has remained unchanged in the last several decades. Immunotherapy is proved to be a promising therapeutic strategy against osteosarcoma, especially for those with metastasis. Our previous study explored the sensibilization of zoledronate (ZOL) in γδ T cell-medi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wang, Shengdong, Li, Hengyuan, Ye, Chenyi, Lin, Peng, Li, Binghao, Zhang, Wei, Sun, Lingling, Wang, Zhan, Xue, Deting, Teng, Wangsiyuan, Zhou, Xingzhi, Lin, Nong, Ye, Zhaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835048/
https://ncbi.nlm.nih.gov/pubmed/29535738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00377
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