Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development

Resistant mouse strains mount a protective T cell-mediated immune response upon infection with Leishmania (L.) parasites. Healing correlates with a T helper (Th) cell-type 1 response characterized by a pronounced IFN-γ production, while susceptibility is associated with an IL-4-dependent Th2-type re...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Zimara, Nicole, Chanyalew, Menberework, Aseffa, Abraham, van Zandbergen, Ger, Lepenies, Bernd, Schmid, Maximilian, Weiss, Richard, Rascle, Anne, Wege, Anja Kathrin, Jantsch, Jonathan, Schatz, Valentin, Brown, Gordon D., Ritter, Uwe
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834765/
https://ncbi.nlm.nih.gov/pubmed/29535708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00263
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