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Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

DNA methylation is an important epigenetic modification involved in gene regulation and transposable element silencing. Changes in DNA methylation can be heritable and, thus, can lead to the formation of stable epialleles. A well-characterized example of a stable epiallele in plants is fwa, which co...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gallego-Bartolomé, Javier, Gardiner, Jason, Liu, Wanlu, Papikian, Ashot, Ghoshal, Basudev, Kuo, Hsuan Yu, Zhao, Jenny Miao-Chi, Segal, David J., Jacobsen, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834696/
https://ncbi.nlm.nih.gov/pubmed/29444862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716945115
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