Locus coeruleus integrity in old age is selectively related to memories linked with salient negative events

The locus coeruleus (LC) is the principal origin of noradrenaline in the brain. LC integrity varies considerably across healthy older individuals, and is suggested to contribute to altered cognitive functions in aging. Here we test this hypothesis using an incidental memory task that is known to be...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hämmerer, Dorothea, Callaghan, Martina F., Hopkins, Alexandra, Kosciessa, Julian, Betts, Matthew, Cardenas-Blanco, Arturo, Kanowski, Martin, Weiskopf, Nikolaus, Dayan, Peter, Dolan, Raymond J., Düzel, Emrah
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834676/
https://ncbi.nlm.nih.gov/pubmed/29440429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712268115
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