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Epigenetic modifiers promote mitochondrial biogenesis and oxidative metabolism leading to enhanced differentiation of neuroprogenitor cells

During neural development, epigenetic modulation of chromatin acetylation is part of a dynamic, sequential and critical process to steer the fate of multipotent neural progenitors toward a specific lineage. Pan-HDAC inhibitors (HDCis) trigger neuronal differentiation by generating an “acetylation” s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Uittenbogaard, Martine, Brantner, Christine A., Chiaramello, Anne
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834638/
https://ncbi.nlm.nih.gov/pubmed/29500414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0396-1
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