Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model

Huntington’s disease (HD) is a monogenic disorder, caused by mutations in the HTT gene which result in expansion of CAG triplets. The product of the mutated gene is misfolded huntingtin protein that forms aggregates leading to impairment of neuronal function, neurodegeneration, motor abnormalities a...

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Detaylı Bibliyografya
Yayımlandı:Neuromolecular Med
Asıl Yazarlar: Pierzynowska, Karolina, Gaffke, Lidia, Hać, Aleksandra, Mantej, Jagoda, Niedziałek, Natalia, Brokowska, Joanna, Węgrzyn, Grzegorz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2018
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834590/
https://ncbi.nlm.nih.gov/pubmed/29435951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-018-8482-1
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