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Item-level analyses reveal genetic heterogeneity in neuroticism

Genome-wide association studies (GWAS) of psychological traits are generally conducted on (dichotomized) sums of items or symptoms (e.g., case-control status), and not on the individual items or symptoms themselves. We conduct large-scale GWAS on 12 neuroticism items and observe notable and replicab...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Nagel, Mats, Watanabe, Kyoko, Stringer, Sven, Posthuma, Danielle, van der Sluis, Sophie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834468/
https://ncbi.nlm.nih.gov/pubmed/29500382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03242-8
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