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Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death

NSAIDs (non-steroidal anti-inflammatory drugs) have potential use as anticancer agents, either alone or in combination with other cancer therapies. We found that NSAIDs including celecoxib (CCB) and ibuprofen (IBU) significantly potentiated the cytotoxicity of Hsp90 inhibitors in human multidrug-res...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Moon, Hyun-Jung, Kim, Hak-Bong, Lee, Su-Hoon, Jeun, So-Eun, Kang, Chi-Dug, Kim, Sun-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834263/
https://ncbi.nlm.nih.gov/pubmed/29541415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24130
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