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Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells
Fusion proteins combining hexavalent TRAIL with antibody fragments allow for a targeted delivery and efficient apoptosis induction in tumor cells. Here, we analyzed scFv-Fc-scTRAIL molecules directed against EGFR, HER2, HER3, and EpCAM as well as an untargeted Fc-scTRAIL fusion protein for their pot...
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| Pubblicato in: | Oncotarget |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834252/ https://ncbi.nlm.nih.gov/pubmed/29541416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24379 |
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