High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary brain malignancy in adults, yet survival outcomes remain poor. First line treatment is well established, however disease invariably recurs and improving prognosis is challenging. With the aim of personalizing therapy at recurrence, we have es...

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Publicado en:PLoS One
Main Authors: Yu, Kenny Kwok-Hei, Taylor, Jessica T., Pathmanaban, Omar N., Youshani, Amir Saam, Beyit, Deniz, Dutko-Gwozdz, Joanna, Benson, Roderick, Griffiths, Gareth, Peers, Ian, Cueppens, Peter, Telfer, Brian A., Williams, Kaye J., McBain, Catherine, Kamaly-Asl, Ian D., Bigger, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834163/
https://ncbi.nlm.nih.gov/pubmed/29499065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193694
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