Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors

BACKGROUND: While patient-derived xenografts (PDXs) offer a powerful modality for translational cancer research, a precise evaluation of how accurately patient responses correlate with matching PDXs in a large, heterogeneous population is needed for assessing the utility of this platform for preclin...

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Bibliographic Details
Published in:Ann Oncol
Main Authors: Izumchenko, E., Paz, K., Ciznadija, D., Sloma, I., Katz, A., Vasquez-Dunddel, D., Ben-Zvi, I., Stebbing, J., McGuire, W., Harris, W., Maki, R., Gaya, A., Bedi, A., Zacharoulis, S., Ravi, R., Wexler, L. H., Hoque, M. O., Rodriguez-Galindo, C., Pass, H., Peled, N., Davies, A., Morris, R., Hidalgo, M., Sidransky, D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834154/
https://ncbi.nlm.nih.gov/pubmed/28945830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx416
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