FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization

Ovarian cancer remains associated with a high mortality rate and relapse is too frequently seen after chemotherapeutic treatment of granulosa cell tumors (GCTs) or epithelial ovarian cancers (EOCs). It is thus of major importance to progress in the knowledge of the molecular mechanisms underlying ch...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Manousakidi, Sevasti, Guillaume, Arnaud, Pirou, Caroline, Bouleau, Sylvina, Mignotte, Bernard, Renaud, Flore, Le Floch, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833868/
https://ncbi.nlm.nih.gov/pubmed/29467390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0033-y
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