FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization

Ovarian cancer remains associated with a high mortality rate and relapse is too frequently seen after chemotherapeutic treatment of granulosa cell tumors (GCTs) or epithelial ovarian cancers (EOCs). It is thus of major importance to progress in the knowledge of the molecular mechanisms underlying ch...

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Vydáno v:Oncogenesis
Hlavní autoři: Manousakidi, Sevasti, Guillaume, Arnaud, Pirou, Caroline, Bouleau, Sylvina, Mignotte, Bernard, Renaud, Flore, Le Floch, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833868/
https://ncbi.nlm.nih.gov/pubmed/29467390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0033-y
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