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Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death

Drug combinations have been increasingly applied in chemotherapy as a strategy to enhance the efficacy of anti-cancer treatment. The appropriate drug combinations may achieve synergistic effects beyond monotherapies alone. AC220 (Quizartinib), an FLT3 receptor tyrosine kinase inhibitor, developed fo...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Ouchida, Amanda Tomie, Li, Yingbo, Geng, Jiefei, Najafov, Ayaz, Ofengeim, Dimitry, Sun, Xiaoxiao, Yu, Qiang, Yuan, Junying
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833862/
https://ncbi.nlm.nih.gov/pubmed/29374185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0170-9
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