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Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk

Intervertebral disc degeneration (IDD) is an important factor leading to low back pain, but the underlying mechanisms remain poorly understood. Compared with normal nucleus pulposus (NP) tissues, the expression of circ-GRB10 was downregulated in IDD. Furthermore, overexpression of circ-GRB10 inhibit...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Guo, Wei, Zhang, Bin, Mu, Kun, Feng, Shi-Qing, Dong, Zhan-Yin, Ning, Guang-Zhi, Li, Hao-Ran, Liu, Shen, Zhao, Ling, Li, Yan, Yu, Bing-Bing, Duan, Hui-Quan, Sun, Chao, Li, Yong-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833826/
https://ncbi.nlm.nih.gov/pubmed/29476072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0232-z
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