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Circular RNA derived from TIMP2 functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR‑185‑5p and matrix metalloproteinase 2

Intervertebral disc degeneration (IDD) is an important cause of lower back pain, although the underlying mechanisms remain poorly understood. The present study aimed to examine the role of a circular RNA derived from tissue inhibitor of metallopeptidases 2 (circ-TIMP2) in degenerative nucleus pulpos...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Guo, Wei, Zhang, Bin, Sun, Chao, Duan, Hui-Quan, Liu, Wei-Xiao, Mu, Kun, Zhao, Ling, Li, Hao-Ran, Dong, Zhan-Yin, Cui, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307854/
https://ncbi.nlm.nih.gov/pubmed/32626912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4621
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