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TACC3 transcriptionally upregulates E2F1 to promote cell growth and confer sensitivity to cisplatin in bladder cancer

Accumulating evidence has shown that transforming acidic coiled-coil 3 (TACC3) is deregulated in a broad spectrum of cancers. In the present study, we reported that TACC3 was markedly elevated in bladder cancer, especially in muscle-invasive bladder cancers (MIBCs). The upregulation of TACC3 was pos...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lin, Zhi-Rui, Wang, Meng-Yao, He, Shi-Yang, Cai, Zhi-Ming, Huang, Wei-Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833822/
https://ncbi.nlm.nih.gov/pubmed/29358577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0112-6
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