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TACC3 transcriptionally upregulates E2F1 to promote cell growth and confer sensitivity to cisplatin in bladder cancer

Accumulating evidence has shown that transforming acidic coiled-coil 3 (TACC3) is deregulated in a broad spectrum of cancers. In the present study, we reported that TACC3 was markedly elevated in bladder cancer, especially in muscle-invasive bladder cancers (MIBCs). The upregulation of TACC3 was pos...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Lin, Zhi-Rui, Wang, Meng-Yao, He, Shi-Yang, Cai, Zhi-Ming, Huang, Wei-Ren
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833822/
https://ncbi.nlm.nih.gov/pubmed/29358577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0112-6
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