Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder in which genetic and environmental factors synergistically lead to loss of midbrain dopamine (DA) neurons. Mutation of leucine-rich repeated kinase2 (Lrrk2) genes is responsible for the majority of inherited familial cases of PD and can also b...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Tozzi, Alessandro, Tantucci, Michela, Marchi, Saverio, Mazzocchetti, Petra, Morari, Michele, Pinton, Paolo, Mancini, Andrea, Calabresi, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833812/
https://ncbi.nlm.nih.gov/pubmed/29434188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0221-2
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky