Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1

Cancer cells utilize lysosomes for invasion and metastasis. Myeloid Zinc Finger1 (MZF1) is an ErbB2-responsive transcription factor that promotes invasion of breast cancer cells via upregulation of lysosomal cathepsins B and L. Here we identify let-7 microRNA, a well-known tumor suppressor in breast...

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Detaylı Bibliyografya
Yayımlandı:Oncogenesis
Asıl Yazarlar: Tvingsholm, Siri Amanda, Hansen, Malene Bredahl, Clemmensen, Knut Kristoffer Bundgaard, Brix, Ditte Marie, Rafn, Bo, Frankel, Lisa B, Louhimo, Riku, Moreira, José, Hautaniemi, Sampsa, Gromova, Irina, Jäättelä, Marja, Kallunki, Tuula
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833801/
https://ncbi.nlm.nih.gov/pubmed/29396433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0014-6
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