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BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis

TAF6δ is a pro-apoptotic splice variant of the RNA polymerase II general transcription factor, TAF6, that can dictate life vs. death decisions in animal cells. TAF6δ stands out from classical pro-apoptotic proteins because it is encoded by a gene that is essential at the cellular level, and because...

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Publicado en:Cell Death Dis
Autores principales: Delannoy, Aurélie, Wilhelm, Emmanuelle, Eilebrecht, Sebastian, Alvarado-Cuevas, Edith Milena, Benecke, Arndt G, Bell, Brendan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833734/
https://ncbi.nlm.nih.gov/pubmed/29358700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0115-3
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