Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers

Estrogen receptor-α positive (ERα+) breast cancer accounts for approximately 70–80% of the nearly 25,0000 new cases of breast cancer diagnosed in the US each year. Endocrine-targeted therapies (those that block ERα activity) serve as the first line of treatment in most cases. Despite the proven bene...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Williams, Michelle M., Lee, Linus, Werfel, Thomas, Joly, Meghan M. Morrison, Hicks, Donna J., Rahman, Bushra, Elion, David, McKernan, Courtney, Sanchez, Violeta, Estrada, Monica V., Massarweh, Suleiman, Elledge, Richard, Duvall, Craig, Cook, Rebecca S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833697/
https://ncbi.nlm.nih.gov/pubmed/29343814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0072-x
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