LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle

Although endometrial cancer is the most common type of gynecological malignancy in developed countries, its molecular etiology is not well understood. Leucine-rich repeat and immunoglobulin-like domain 2 (LRIG2) is an evolutionarily conserved gene, but its functions in the endometrium are unknown. I...

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Veröffentlicht in:Oncogenesis
Hauptverfasser: Suh, Dae-Shik, Park, Si Eun, Jin, Hanyong, Lee, Kangseok, Bae, Jeehyeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833696/
https://ncbi.nlm.nih.gov/pubmed/29358688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0019-1
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