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NDRG2 contributes to cisplatin sensitivity through modulation of BAK-to-Mcl-1 ratio

The downregulation of N-Myc downstream-regulated gene 2 (NDRG2) is known to be associated with the progression and poor prognosis of several cancers. Sensitivity to anti-cancer may be associated with a good prognosis in cancer patients, and NDRG2, which is induced by p53, sensitizes the cells to che...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Park, Soojong, Oh, Sang-Seok, Lee, Ki Won, Lee, Yeon-Kyeong, Kim, Nae Yu, Kim, Joo Heon, Yoo, Jiyun, Kim, Kwang Dong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833685/
https://ncbi.nlm.nih.gov/pubmed/29348517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0184-3
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