Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart

Our previous studies showed that both exogenous and endogenous FGF21 inhibited cardiac apoptosis at the early stage of type 1 diabetes. Whether FGF21 induces preventive effect on type 2 diabetes-induced cardiomyopathy was investigated in the present study. High-fat-diet/streptozotocin-induced type 2...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Yang, Hong, Feng, Anyun, Lin, Sundong, Yu, Lechu, Lin, Xiufei, Yan, Xiaoqing, Lu, Xuemian, Zhang, Chi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833682/
https://ncbi.nlm.nih.gov/pubmed/29445083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0307-5
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