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Nucleolin and ErbB2 inhibition reduces tumorigenicity of ErbB2-positive breast cancer
ErbB2, a member of the ErbB family of receptor tyrosine kinases, is an essential player in the cell’s growth and proliferation signaling pathways. Amplification or overexpression of ErbB2 is observed in ∼30% of breast cancer patients, and often drives cellular transformation and cancer development....
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833446/ https://ncbi.nlm.nih.gov/pubmed/29352243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0067-7 |
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