The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity

HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small nucleotide polymorphisms (SNPs) in the HMG20A gene have been linked to type 2 diabetes mellitus (T2DM) yet neither expression nor function of this T2DM candidate gene in islets is k...

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Vydáno v:Cell Death Dis
Hlavní autoři: Mellado-Gil, Jose M., Fuente-Martín, Esther, Lorenzo, Petra I., Cobo-Vuilleumier, Nadia, López-Noriega, Livia, Martín-Montalvo, Alejandro, Gómez, Irene de Gracia Herrera, Ceballos-Chávez, Maria, Gómez-Jaramillo, Laura, Campos-Caro, Antonio, Romero-Zerbo, Silvana Y., Rodríguez-Comas, Júlia, Servitja, Joan-Marc, Rojo-Martinez, Gemma, Hmadcha, Abdelkrim, Soria, Bernat, Bugliani, Marco, Marchetti, Piero, Bérmudez-Silva, Francisco J., Reyes, Jose C., Aguilar-Diosdado, Manuel, Gauthier, Benoit R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833347/
https://ncbi.nlm.nih.gov/pubmed/29449530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0272-z
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