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A stochastic and dynamical view of pluripotency in mouse embryonic stem cells

Pluripotent embryonic stem cells are of paramount importance for biomedical sciences because of their innate ability for self-renewal and differentiation into all major cell lines. The fateful decision to exit or remain in the pluripotent state is regulated by complex genetic regulatory networks. Th...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Lin, Yen Ting, Hufton, Peter G., Lee, Esther J., Potoyan, Davit A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833290/
https://ncbi.nlm.nih.gov/pubmed/29451874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006000
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