Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet

AIMS: Abdominal aortic aneurysm (AAA) is an age-associated disease characterized by chronic inflammation, vascular cell apoptosis and metalloproteinase-mediated extracellular matrix degradation. Despite considerable progress in identifying targets involved in these processes, therapeutic approaches...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Metghalchi, Sarvenaz, Vandestienne, Marie, Haddad, Yacine, Esposito, Bruno, Dairou, Julien, Tedgui, Alain, Mallat, Ziad, Potteaux, Stephane, Taleb, Soraya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833272/
https://ncbi.nlm.nih.gov/pubmed/29494675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193737
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