RNA-directed DNA methylation involves co-transcriptional small RNA-guided slicing of Pol V transcripts in Arabidopsis

Small RNAs regulate chromatin modifications such as DNA methylation and gene silencing across eukaryotic genomes. In plants, RNA-directed DNA methylation (RdDM) requires 24-nucleotide (nt) small RNAs (siRNAs) that bind ARGONAUTE4 (AGO4) and target genomic regions for silencing. It also requires non-...

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Gepubliceerd in:Nat Plants
Hoofdauteurs: Liu, Wanlu, Duttke, Sascha H., Hetzel, Jonathan, Groth, Martin, Feng, Suhua, Gallego-Bartolome, Javier, Zhong, Zhenhui, Kuo, Hsuan Yu, Wang, Zonghua, Zhai, Jixian, Chory, Joanne, Jacobsen, Steven E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832601/
https://ncbi.nlm.nih.gov/pubmed/29379150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41477-017-0100-y
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