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An adipo-biliary-uridine axis that regulates energy homeostasis

Uridine, a pyrimidine nucleoside present at high levels in the plasma of rodents and humans, is critical for RNA synthesis, glycogen deposition, and many other essential cellular processes. It also contributes to systemic metabolism, but the underlying mechanisms remain unclear. We found that plasma...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Deng, Yingfeng, Wang, Zhao V., Gordillo, Ruth, An, Yu, Zhang, Chen, Liang, Qiren, Yoshino, Jun, Cautivo, Kelly M., De Brabander, Jef, Elmquist, Joel K., Horton, Jay D., Hill, Joseph A., Klein, Samuel, Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832364/
https://ncbi.nlm.nih.gov/pubmed/28302796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf5375
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