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Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways

Defects in p53 and nuclear factor-kappa B (NF-κB) signaling pathways are frequently observed in the initiation and development of various human malignancies, including prostate cancer. Clinical studies demonstrate higher expression of NF-κB/p65/RelA, NF-κB/p50/RelB, and cRel as well as downregulatio...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Shankar, Eswar, Zhang, Ailin, Franco, Daniel, Gupta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832059/
https://ncbi.nlm.nih.gov/pubmed/28208611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020264
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