Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma

To investigate whether mutation profiling and microsatellite instability (MSI) status were associated with clinicopathological features and the prognosis in metastatic colorectal cancer (mCRC), mutations in RAS (including KRAS, NRAS, and HRAS) and BRAF were determined by Sanger sequencing. Tumor mis...

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Bibliographische Detailangaben
Veröffentlicht in:Gastroenterol Res Pract
Hauptverfasser: Liu, Jianhua, Zeng, Weiqiang, Huang, Chengzhi, Wang, Junjiang, Yang, Dongyang, Ma, Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831938/
https://ncbi.nlm.nih.gov/pubmed/29643917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4585802
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