Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma

To investigate whether mutation profiling and microsatellite instability (MSI) status were associated with clinicopathological features and the prognosis in metastatic colorectal cancer (mCRC), mutations in RAS (including KRAS, NRAS, and HRAS) and BRAF were determined by Sanger sequencing. Tumor mis...

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Detalles Bibliográficos
Publicado en:Gastroenterol Res Pract
Main Authors: Liu, Jianhua, Zeng, Weiqiang, Huang, Chengzhi, Wang, Junjiang, Yang, Dongyang, Ma, Dong
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831938/
https://ncbi.nlm.nih.gov/pubmed/29643917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4585802
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