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Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma

To investigate whether mutation profiling and microsatellite instability (MSI) status were associated with clinicopathological features and the prognosis in metastatic colorectal cancer (mCRC), mutations in RAS (including KRAS, NRAS, and HRAS) and BRAF were determined by Sanger sequencing. Tumor mis...

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Bibliografske podrobnosti
izdano v:Gastroenterol Res Pract
Main Authors: Liu, Jianhua, Zeng, Weiqiang, Huang, Chengzhi, Wang, Junjiang, Yang, Dongyang, Ma, Dong
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831938/
https://ncbi.nlm.nih.gov/pubmed/29643917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4585802
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