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Creating a more robust 5-hydroxymethylfurfural oxidase by combining computational predictions with a novel effective library design

BACKGROUND: HMF oxidase (HMFO) from Methylovorus sp. is a recently characterized flavoprotein oxidase. HMFO is a remarkable enzyme as it is able to oxidize 5-hydroxymethylfurfural (HMF) into 2,5-furandicarboxylic acid (FDCA): a catalytic cascade of three oxidation steps. Because HMF can be formed fr...

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Detalhes bibliográficos
Publicado no:Biotechnol Biofuels
Main Authors: Martin, Caterina, Ovalle Maqueo, Amaury, Wijma, Hein J., Fraaije, Marco W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831843/
https://ncbi.nlm.nih.gov/pubmed/29507608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1051-x
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