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Creating a more robust 5-hydroxymethylfurfural oxidase by combining computational predictions with a novel effective library design
BACKGROUND: HMF oxidase (HMFO) from Methylovorus sp. is a recently characterized flavoprotein oxidase. HMFO is a remarkable enzyme as it is able to oxidize 5-hydroxymethylfurfural (HMF) into 2,5-furandicarboxylic acid (FDCA): a catalytic cascade of three oxidation steps. Because HMF can be formed fr...
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Publicado no: | Biotechnol Biofuels |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831843/ https://ncbi.nlm.nih.gov/pubmed/29507608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1051-x |
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