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Mechanism of inhibition of translation termination by blasticidin S

Understanding the mechanisms of inhibitors of translation termination may inform development of new antibacterials and therapeutics for premature-termination diseases. We report the crystal structure of the potent termination inhibitor BlaS bound to the ribosomal 70S•RF1 termination complex. BlaS sh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Biol
Prif Awduron: Svidritskiy, Egor, Korostelev, Andrei A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831496/
https://ncbi.nlm.nih.gov/pubmed/29366636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.01.007
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