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Does the rising placebo response impact antihypertensive clinical trial outcomes? An analysis of data from the Food and Drug Administration 1990-2016

BACKGROUND: Recent studies show that placebo response has grown significantly over time in clinical trials for antidepressants, ADHD medications, antiepileptics, and antidiabetics. Contrary to expectations, trial outcome measures and success rates have not been impacted. This study aimed to see if t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Khan, Arif, Fahl Mar, Kaysee, Schilling, Joshua, Brown, Walter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831097/
https://ncbi.nlm.nih.gov/pubmed/29489874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193043
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