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Does the rising placebo response impact antihypertensive clinical trial outcomes? An analysis of data from the Food and Drug Administration 1990-2016

BACKGROUND: Recent studies show that placebo response has grown significantly over time in clinical trials for antidepressants, ADHD medications, antiepileptics, and antidiabetics. Contrary to expectations, trial outcome measures and success rates have not been impacted. This study aimed to see if t...

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Pubblicato in:PLoS One
Autori principali: Khan, Arif, Fahl Mar, Kaysee, Schilling, Joshua, Brown, Walter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831097/
https://ncbi.nlm.nih.gov/pubmed/29489874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193043
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