Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice

Increasingly, evidence suggests that exposure to maternal obesity creates an inflammatory environment in utero, exerting long‐lasting postnatal signatures on the juvenile innate immune system and microbiome that may predispose offspring to development of fatty liver disease. We found that exposure t...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Friedman, Jacob E., Dobrinskikh, Evgenia, Alfonso‐Garcia, Alba, Fast, Alexander, Janssen, Rachel C., Soderborg, Taylor K., Anderson, Aimee L., Reisz, Julie A., D'Alessandro, Angelo, Frank, Daniel N., Robertson, Charles E., de la Houssaye, Becky A., Johnson, Linda K., Orlicky, David J., Wang, Xiaoxin X., Levi, Moshe, Potma, Eric O., El Kasmi, Karim C., Jonscher, Karen R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831029/
https://ncbi.nlm.nih.gov/pubmed/29507905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1139
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