Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice

Increasingly, evidence suggests that exposure to maternal obesity creates an inflammatory environment in utero, exerting long‐lasting postnatal signatures on the juvenile innate immune system and microbiome that may predispose offspring to development of fatty liver disease. We found that exposure t...

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Pubblicato in:Hepatol Commun
Autori principali: Friedman, Jacob E., Dobrinskikh, Evgenia, Alfonso‐Garcia, Alba, Fast, Alexander, Janssen, Rachel C., Soderborg, Taylor K., Anderson, Aimee L., Reisz, Julie A., D'Alessandro, Angelo, Frank, Daniel N., Robertson, Charles E., de la Houssaye, Becky A., Johnson, Linda K., Orlicky, David J., Wang, Xiaoxin X., Levi, Moshe, Potma, Eric O., El Kasmi, Karim C., Jonscher, Karen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831029/
https://ncbi.nlm.nih.gov/pubmed/29507905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1139
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